Serving Size: 1 Capsule... %DV
Lactoferrin... 250 mg... †
† Daily Value not established
What Is It?
Lactoferrin is an iron-binding glycoprotein found in human body fluids, human milk and bovine milk. Bovine lactoferrin is capable of interacting with human lactoferrin binding sites. Lactoferrin's acitivity comes from the 52 first amino acids in the peptide sequence. The sequence is identical for bovine and human lactoferrin. Lactoferrin is also extremely resistant to degradation in the gastrointestinal tract, being effective both in acidic or alkaline pH, and is absorbed by a specific receptor found in the intestinal brush border.
What Does It Do?
Primary Uses: Lactoferrin is a powerful immune booster. Its multifunctional role also encompasses antibacterial, antiviral, antifungal, antioxidant and immunomodulatory activities. Lactoferrin has been used successfully as an adjunct to chemotherapy to improve the immunity of cancer patients and to reduce the treatment side effects. Neonatal units successfully use lactoferrin to help reduce neonate infection in hospitals, and baby formulas manufactured in China are now being supplemented with lactoferrin.
Secondary Uses: Being an immunomodulator, lactoferrin helps manage the inflammatory response. Inflammatory conditions that can benefit from lactoferrin include high cholesterol, gastrointestinal inflammation, respiratory tract inflammation and acne. Lactoferrin may also stimulate the cells responsible for bone growth.
Who Should Take It?
Anyone can take this supplement to support the immune system against illness and infection. Lactoferrin contains no lactose and contains little to no casein, so it is safe for those with a lactose intolerance who want to reap some of the benefits of dairy without having to consume lactose-containing dairy products.
Take 1-6 capsules daily in divided doses with meals, a few hours before or after taking other medications, or as directed by a qualified health care practitioner.
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Grey A, Banovic T, Zhu Q, Watson M, Callon K, Palmano K, Ross J, Naot D, Reid IR, Cornish J. The low-density lipoprotein receptor-related protein 1 is a mitogenic receptor for lactoferrin in osteoblastic cells. Mol Endocrinol. 2004 Sep;18(9):2268-78. Epub 2004 Jun 3.
Weinberg ED. Human lactoferrin: a novel therapeutic with broad spectrum potential. J Pharm Pharmacol. 2001 Oct;53(10):1303-10. Review.
Zagulski T, Lipinski P, Zagulska A, Broniek S, Jarzabeck Z. Lactoferrin can protect mice against a lethal dose of Escherichia coli in experimental infection in vivo. Br. J. Exp. Path. (1989) 70. 697-704.
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