• Network antioxidant
• Mitochondrial function
• Cognitive support
• Neurological function
What Is It?
In 1999, AOR introduced the world's first pure R(+) lipoic acid based on the most current research. Unlike most conventional alpha-lipoic acid supplements, AOR's 95% pure R( α ) lipoic acid delivers the most effective form of this valuable antioxidant without the negative actions of S(-) lipoic acid.
What Does It Do?
Primary Uses: This powerful anti-aging nutrient has been shown to mimic some of the effects of caloric restriction, the only proven method of extending health span and lifespan. It does so by protecting the mitochondria against free radical damage. A study in a short-lived strain of mice demonstrated that R-lipoic acid can dramatically increase its lifespan. Neither S-lipoic acid nor conventional alpha-lipoic acid had any significant effect. R-Lipoic acid is a versatile antioxidant known for its ability to protect the brain and nerve cells from free radicals and heavy metals such as iron that have been linked to cognitive and neurodegenerative diseases.
Secondary Uses: Lipoic acid has also been shown to help reduce blood sugar levels, protect against nerve damage resulting from hyperglycemia (neuropathy) and support weight loss in higher doses.
Who Should Take It?
R-Lipoic acid is a powerful, natural and well-rounded antioxidant for those looking for “fountain-of-youth” supplements that also help protect the brain, nerves and metabolic health. Regular doses of lipoic acid are recommended for maintaining overall general health while high doses of R(+) lipoic acid are recommended for the management of high blood sugar, diabetic neuropathy and weight.
Take 1 capsule three times daily with/without food, or as directed by a qualified health care practitioner.
Hagen TM, Ingersoll RT, Lykkesfeldt J, Liu J, Wehr CM, Vinarsky V, Bartholomew JC, Ames AB. “
(R)-alpha-lipoic acid-supplemented old rats have improved mitochondrial function, decreased oxidative damage, and increased metabolic rate.”
FASEB J. 1999 Feb; 13(2): 411-8.
Hagen TM, Vinarsky V, Wehr CM, Ames BN. “
(R)-alpha-lipoic acid reverses the age-associated increase in susceptibility of hepatocytes to tert-butylhydroperoxide both in vitro and in vivo.”
Antioxid Redox Signal. 2000 Fall; 2(3): 473-83.
Lockhart B, Jones C, Cuisinier C, Villain N, Peyroulan D, Lestage P. “
Inhibition of L-homocysteic acid and buthionine sulphoximine-mediated neurotoxicity in rat embryonic neuronal cultures with alpha-lipoic acid enantiomers.”
Brain Res. 2000 Feb 14; 855(2): 292-7.
Streeper RS, Henriksen EJ, Jacob S, Hokama JY, Fogt DL, Tritschler HJ. “
Differential effects of lipoic acid stereoisomers on glucose metabolism in insulin-resistant skeletal muscle.”
Am J Physiol. 1997 Jul; 273(1 Pt 1): E185-91.
Suh J, Rocha A, Shigeno E, Frei B, Hagen TM. “
(R)-alpha-lipoic acid supplementation of old rats decreases age-dependent accumulation of iron and ascorbate depletion in brain.”
AGE. 1999 Jul; 22(3): 121(Abs 19).
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