Serving Size: 1 Capsule
L-5-Hydroxytryptophan (5-HTP) … 50 mg
Non-medicinal ingredients: microcrystalline cellulose, ascorbyl palmitate. Capsule: hypromellose.
AOR Guarantees: that no ingredients not listed on the label have been added to the product. Contains no wheat, gluten, corn, nuts, peanuts, sesame seeds, sulphites, mustard, dairy, soy, eggs, fish or shellfish.
Source: Griffonia simplicifolia seed
What Is It?
Tryfonia is L-5-hydroxytryptophan (5-HTP) derived from Griffonia simplicifolia seed extract. 5-HTP is a metabolite of the amino acid tryptophan, and an essential precursor of the neurotransmitter serotonin and the neurohormone melatonin.
What Does It Do?Primary Uses: 5-HTP is primarily used to support mood through its ability to boost serotonin levels. 5-HTP has been compared to various tricyclic antidepressants and has been found to be as effective with fewer side effects and quicker effectiveness. Since serotonin and melatonin are also involved in regulating the sleep/wake cycle, 5-HTP may enhance sleep quality.Secondary Uses: Research supports a role for 5-HTP in reducing headaches and the symptoms of fibromyalgia. Studies in Spain and Italy found that 5-HTP was comparable to the drug methysergide in alleviating the symptoms of migraines (over 70% in both groups) while eliciting considerably fewer side effects. Fibromyalgia patients have been found to have low serotonin levels and have shown symptomatic improvement with the use of tricyclic and SSRI antidepressants. Several clinical trials have confirmed significant improvement in symptoms, including pain, morning stiffness, nervousness, and fatigue.
Who Should Take It?
Those who suffer with nervousness, mood imbalances, fibromyalgia or sleep disorders may benefit from taking 5-HTP. Tryfonia MAX is twice the strength of regular Tryfonia.
For healthy mood balance, take 1-2 capsules 3 times daily with food; for relief of symptoms of fibromyalgia, take 2 capsules 3-4 times daily with food. To minimize gastrointestinal side effect risk, start at 50-100mg, 2-3 times daily and slowly increase to an effective dose over 2 weeks. Use for a minimum of 1 week to see beneficial effects for mood balance and 2 weeks for the alleviation of fibromyalgia symptoms. Consult a health care practitioner if symptoms persist or worsen and for use beyond one year.
Cautions: Consult a health care practitioner prior to use if taking carbidopa or drugs/supplements with serotonergic activity. These may include, but are not limited to, L-tryptophan, S-adenosylmethionine (SAMe), St. John's Wort, antidepressants, pain killers, cough/cold medication containing dextromethorphan, anti-nausea medication and anti-migraine medication. Discontinue use and consult a health care practitioner if you show signs of weakness, oral ulcers, or abdominal pain accompanied by severe muscle pain or if you experience skin changes. Some people may experience gastrointestinal disturbances such as diarrhea, nausea, vomiting and abdominal pain as well as drowsiness. Do not use if you have scleroderma. Exercise caution if driving or operating heavy machinery or engaging in activities requiring mental alertness. Not to be used by individuals under the age of 18 or those with a medical condition.
Pregnancy/Nursing: Do not take if pregnant, nursing or trying to conceive
Camsi I, et al., (1990). Double-blind study of 5-hydroxy-tryptophan versus placebo in the treatment of primary fibromyalgia syndrome. J.Int. Med. Res; 18: 201-209.
Lance JW. (1991). 5-HTP and its role in migraine. Eur Neurol; 31: 279-281.
Podunger W, et al. (1991). A functional-dimensional approach to depression: serotonin deficiency as a target syndrome in a comparison of 5-hydroxytrophin and fluvoxamine. Psychopathology; 24: 53-81.
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