• Elevated uric acid levels
Serving Size: 3 Capsules... %DV
White Mulberry... 1500 mg... †
trans-Resveratrol... 40 mg... †
Grape Seed extract... 50 mg... †
( 85% oligomeric proanthocyanidins)
† Daily Value not established
What Is It?
Urica combines a high dose of morin-rich mulberry extract with supportive doses of resveratrol and grape seed extract.
What Does It Do?
Primary Uses: Urica is designed to reduce uric acid levels in the body, thereby reducing the risk of gout. Gout develops from high uric acid levels which form crystals that are deposited in the cartilage of the joints, leading to extremely painful inflammation and swelling of the joints. The most common target of gout is the joints of the big toe and feet. Morin acts on the kidneys to inhibit uric acid reabsorption and thus promote the excretion of uric acid from the body. Secondly, it inhibits the enzyme xanthine oxidase, which converts certain compounds into uric acid. Polyphenols from resveratrol and grape seed extract also act on the kidneys and reduce xanthine oxidase activity. Gout is often associated with a high consumption of fat, protein and alcohol.
Who Should Take It?
This formula may benefit those with gout, high uric acid levels or kidney dysfunction.
Take 3 capsules daily with/without food, or as directed by a qualified health care practitioner.
Du Y, et al. Grape seed polyphenols protect cardiac cells from apoptosis via induction of endogenous antioxidant enzymes. J Agric Food Chem. 2007 Mar 7;55(5):1695-701.
Jia Z, et al. EPR studies on the superoxide-scavenging capacity of the nutraceutical resveratrol. Mol Cell Biochem. 2008 Jun;313(1-2):187-94.
Sonlimar M and Sarmalina S. Effect of Grape (Vitis vinifera L.) Seed on Reducing Serum Uric Acid Level in Gout-Animals Model. Majalah Kesehatan PharmaMedika, 2010 Vol.2, No.1: 106-109.
Yu Z, et al. Morin (3,5,7,2′,4′-pentahydroxyflavone) exhibits potent inhibitory actions on urate transport by the human urate anion transporter (hURAT1) expressed in human embryonic kidney cells. Drug Metab Dispos. 2007 Jun;35(6):981-6.
Yu Z, et al. The dual actions of morin (3,5,7,2′,4′-pentahydroxyflavone) as a hypouricemic agent: uricosuric effect and xanthine oxidase inhibitory activity. J Pharmacol Exp Ther. 2006 Jan;316(1):169-75.
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