• Joint pain
Devil's Claw dry extract (Harpagophytum procumbens)
Root (1.5–3.0:1)…480 mg, equivalent to 720–1440 mg root
Used to help treat joint pain and inflammation including osteo-arthritic pain. Used in Herbal Medicine to help relieve joint pain associated with osteoarthritis.
Adults: Take 1 tablets twice daily with water, before meals.
Duration of use: Minimum 2 to 3 months.
Avoid in cases of known allergies to any of the ingredients in the product. Consult a health care practitioner if symptoms persist. Consult a health care practitioner if symptoms worsen. Consult a health care practitioner prior to use if you are pregnant or breastfeeding..
Do not use if safety seal is broken. Keep out of reach of children.
1- Loew D, Mollerfeld J, Schrodter A et al. Investigations on the pharmacokinetic properties of Harpagophytum extracts and their effects on eicosanoid biosynthesis in vitro and ex vivo. Clin Pharmacol Ther 2001 May;69(5):356-64
2- Occhiuto F et al. A drug used in traditional medicine: Harpagophytum procumbens DC. IV. Effects on some isolated muscle preparations. J Ethnopharmacol 1985;13:201-8.
3- Kaszkin M, Degenring FH, Suter A et al. Anti-inflammatory Activity of The Newly Developed Harpagophytum procumbens Extracts. Poster presentation 6th ESCOP Symposium, Bonn 2001
4- Chantre P, Cappelaere A, Leblan D et al. Efficacy and tolerance of Harpagophytum procumbens versus diacerhein in treatment of osteoarthritis. Phytomedicine 2000 Jun;7(3):177-83
5- Chrubasik S, Junck H, Breitschwerdt H et al. Effectiveness of Harpagophytum extract WS 1531 in the treatment of exacerbation of low back pain: a randomized, placebo-controlled, double-blind study. Eur J Anaesthesiol 1999 Feb;16(2):118-29
6- Chrubasik S, Model A, Black A, Pollak S. A randomized double-blind pilot study comparing Doloteffin((R)) and Vioxx((R)) in the treatment of low back pain. Rheumatology (Oxford) 2003 Jan;42(1):141-8
7- Chrubasik S, Thanner J, Kunzel O et al. Comparison of outcome measures during treatment with the proprietary Harpagophytum extract doloteffin in patients with pain in the lower back, knee or hip. Phytomedicine 2000 Apr;9(3):181-94
8. Gobel H, Heinze A, Ingwersen M et al. [Effects of Harpagophytum procumbens LI 174 (devil's claw) on sensory, motor und vascular muscle reagibility in the treatment of unspecific back pain] [Article in German] Schmerz 2001 Feb;15(1):10-8
9- Laudahn D, Walper A. Efficacy and tolerance of Harpagophytum extract LI 174 in patients with chronic non-radicular back pain. Phytother Res 2001 Nov;15(7):621-4
10- Shaw D, et al. Traditional remedies and food supplements: a 5-year toxicological study (1991-1995). Drug Safety 1997;17:342-56.
11- The Complete German Commission E Monographs, Therapeutic Guide to Herbal Medicines. Blumenthal M et al. 1998. American Botanical Council, 6200 Manor Rd, Austin, Texas, 78723
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