• Sleep disorders
Dry extract of organically grown* fresh flowers and aerial parts of St. John's Wort (Hypericum perforatum L) ...40.24 – 73.22 mg.
Each tablet is standardized to 0.33 mg of hypericin.
* Certified by Bio Suisse
Traditionally used as a sedative to relieve restlessness
or nervousness. Help to treat symptoms of sleep disorders.
Adults: Take 1 tablet, 3 times daily with water, 30 minutes before meals.
Duration of use: May be used for up to 6 weeks.
Avoid prolonged exposure to sunlight, ultraviolet (UV) light or UV therapy.
Consult a healthcare practitioner if you experience sleep disturbances or if you are taking conventional medication such as contraceptives, HIV-1 protease inhibitors, non-nucleoside reverse transcriptase inhibitors, immunosuppressants, anticoagulants, digoxin, theophylline, serotonergic antidepressants, migraine therapies, SSRIs and/or antiepilepsy drugs.
Do not use if you are pregnant or nursing.
Avoid taking in case of known allergy to any of the ingredients in the product.
Consult a healthcare practitioner if symptoms persist.
1-Natural Medicines Comprehensive Database 2001. Pharmacist's Letter 3120 W. March Lane, PO Box 8190, Stockton, CA 95208.
2-The Complete German Commission E Monographs, Therapeutic Guide to Herbal Medicines. Blumenthal M et al. 1998. American Botanical Council, 6200 Manor Rd, Austin, Texas, 78723.
3-Schrader E. Equivalence of St John's wort extract (Ze 117) and fluoxetine: a randomized, controlled study in mild-moderate depression. Int Clin Psychopharmacol 2000 Mar;15(2):61-8
4-Philipp M, Kohnen R, Hiller KO. Hypericum extract versus imipramine or placebo in patients with moderate depression: randomised multicentre study of treatment for eight weeks. BMJ 1999 Dec 11;319(7224):1534-8
5-Lenoir S, Degenring FH, Sller R. ComprimÉs Hyperiforce® pour le traitement de dÉpressions lÉgÈres À modÉrÉes. Schweiz Zschr GanzheitsMedizin 1997;9(5):226-232.
6-Obach RS. Inhibition of human cytochrome P450 enzymes by constituents of St. Johns Wort, an herbal preparation used in the treatment of depression. J Pharmacol Exp Ther 2000;294:88-95.
7-Gurley BJ, Gardner SF, Hubbard MA. Clinical assessment of potential cytochrome P450-mediated herb-drug interactions. AAPS Annual Meeting & Exposition, Oct. 29 - Nov. 2, 2000, Indianapolis, IN:poster (presentation number 3460).
8-Durr D, Stieger B, Kullak-Ublick GA, et al St John's Wort induces intestinal P-glycoprotein/MDR1 and intestinal and hepatic CYP3A4. Clin Pharmacol Ther 2000;68:598-604.
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