Basic concepts and physiologic function, D-glucaric acid is naturally found within the human body and is also present in some foods, particularly vegetables. D-glucaric acid plays an important role in the detoxification process, by promoting the conjugation of endogenous substances such as hormones and exogenous substances such as pollution so that these substances can then be excreted in the bile or urine. Secondly, a metabolite of D-glucaric acid inhibits the enzyme beta-glucaronidase which would otherwise cleave detoxified poisons from their hydrophilic conjugate, allowing the intestinal reabsorption of the toxin
1 capsule two (2) times each day as a dietary supplement or as otherwise directed by a health care professional.
Independent research and additional information
Walaszek Z, Szemraj J, Narog M, Adams AK, Kilgore J, Sherman U, Hanausek M. Metabolism, uptake, and excretion of a D-glucaric acid salt and its potential use in cancer prevention. Cancer Detect Prev. 1997;21( 2):178-90
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