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To support estrogen metabolism*
• maintains optimal 2-hydroxy/16-hydroxy estrogen ratios*
• found in cabbage family vegetables, it's a source of DIM
• nutritional support for liver detoxification*
• made without flowing agents that can inhibit bioavailability
One Capsule Contains:
Indole-3-Carbinol / Diindolylmethane (DIM) complex 200 mg.
Other Ingredients: Hypromellose (derived from cellulose) capsule, Microcrystalline Cellulose, Leucine, Silicon Dioxide.
Indole-3-carbinol (I3C) is a compound found in high concentrations in vegetables of the Brassica family, including broccoli, cauliflower, Brussels sprouts, and cabbage.
As a dietary supplement, I3C provides key nutritional support for liver detoxification.* It also plays an important role in supporting female reproductive health.* The majority of ingested I3C is absorbed in the small intestine as diindolylmethane (DIM), which is thought to be the primary contributor to I3C's beneficial properties. DIM has been shown to selectively bind to estrogen receptors and may act as an estrogen antagonist at physiological concentration.*
In the liver, I3C promotes the metabolism of estrogen and increases the ratio of 2-hydroxy estrogen to 16-hydroxy estrogen.* The 2-hydroxy estrogens, less active than the 16-hydroxy estrogens, generally are eliminated more rapidly from the body. One prospective study found postmenopausal women with the most favorable urinary 2:16-hydroxyestrone ratio were most likely to maintain good female health.*
Preliminary studies have examined the efficacy, safety, and optimal supplementation of I3C. A 12-week phase I trial conducted on 17 women found a 66-percent increase in urinary 2:16-hydroxyestrone ratio with administration of 400 mg I3C daily.*
60 Vegetarian Capsules
Take 1 capsule one to two times daily or as recommended by a health-care practitioner.
ALLERGY WARNING This product is contraindicated in an individual with a history of hypersensitivity to any of its ingredients. EXCIPIENT FREE This product does not contain wheat, gluten, corn, yeast, soy, egg, dairy products, or artificial colors, sweeteners, or flavors. This product also does not contain lactose, palmitic acid, or magnesium, calcium, or vegetable stearates. PREGNANCY If pregnant, consult your health-care practitioner before using this product. INTERACTIONS There are no known adverse interactions or contraindications at publication date.
Disclaimer: This content is subject to change. The information is intended to inform and educate; it does not replace the medical evaluation, advice, diagnosis or treatment by a healthcare professional. www.nhpassist.com © 2014 NDAssist Inc. and/or its affiliates. All rights reserved.
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Indole-3-CarbinolIndications To support estrogen metabolism* IngredientsOne Capsule Contains: Quantity
DoseTake 1 capsule one to two times daily or as recommended by a health-care practitioner. Potential side effects/SafetyALLERGY WARNING This product is contraindicated in an individual with a history of hypersensitivity to any of its ingredients. EXCIPIENT FREE This product does not contain wheat, gluten, corn, yeast, soy, egg, dairy products, or artificial colors, sweeteners, or flavors. This product also does not contain lactose, palmitic acid, or magnesium, calcium, or vegetable stearates. PREGNANCY If pregnant, consult your health-care practitioner before using this product. INTERACTIONS There are no known adverse interactions or contraindications at publication date. |
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