Indications

• botanical extracts to support the body's normal inflammatory response*
• with well-absorbed Meriva® curcumin phytosome*
• minimizes post-operative / post-injury bruising and swelling*
• helps prevent connective tissue breakdown*
• can be used in conjunction with Traumogen and Meriva to promote healing *

Ingredients

Two Capsules Contain:
Bromelain* 250 mg
Curcumin Phytosome** (Curcuma longa extract (root) / Phosphatidylcholine complex) 250 mg
Indian Frankincense extract (gum) (Boswellia serrata) 250 mg
Picrorhiza extract (root) (Picrorhiza kurrooa) 250 mg

Other Ingredients:
Hypromellose (derived from cellulose) capsule, Leucine, Silicon Dioxide.*Bromelain is derived from the pineapple plant (Ananas comosus). This product is not diluted with lactose.**This product uses Indena S.p.A.'s curcumin phytosome (Meriva®). Meriva is a registered trademark of Indena S.p.A.Boswellia standardized to Beta Boswellic Acids 20%. Picrorhiza standardized to Kutkin 4%. Contains ingredient derived from soy (phytosome).

Description

Phytoprofen is a combination of botanicals, including a synergistic blend of the Ayurvedic herbs - Picrorhiza, Boswellia, and curcumin (from turmeric) - all of which support the body's normal inflammatory response.* To these botanicals is added bromelain - a protein-digesting enzyme complex from pineapple that studies have shown can reduce bruising after injury.*

The botanical extracts in Phytoprofen also can minimize post-operative / post-injury bruising and swelling.* Supplementation with bromelain following blunt injuries to the musculoskeletal system resulted in reductions in swelling and tenderness.

A recent in vivo study examined Boswellia extract for its effect on glycosaminoglycan metabolism. Glycosaminoglycans form an important component of the body's connective tissues. Boswellia significantly reduced the degradation of glycosaminoglycans compared to controls.*

Meriva, curcumin phytosome, demonstrates superior bioavailability compared to ordinary curcumin.* Significantly greater amounts are absorbed and taken up by the liver.* A 2007 study published in the journal, Cancer Chemotherapy and Pharmacology, demonstrated Meriva's superior bioavailability compared to ordinary curcumin. This animal study indicated a significantly greater plasma concentration time curve, with an area under the curve (AUC) five times higher for Meriva. Liver levels of curcumin were also higher with Meriva supplementation.* A recent human study (not yet published) demonstrated even greater bioavailability.* Meriva supplementation resulted in significantly better absorption than with ordinary curcumin dosing. *

Dose

Take 2 capsules two to three times daily or as recommended by a health-care practitioner.

Servings Per Container: 30

Potential side effects/Safety

ALLERGY WARNING
This product is contraindicated in an individual with a history of hypersensitivity to any of its ingredients.Phytoprofen contains curcumin phytosome, a plant extract complexed with phosphatidylcholine, which is derived from soy. Phosphatidylcholine contains no soy protein. There are no other soy-based ingredients in Phytoprofen.

PURITY
This product does not contain wheat, gluten, corn, yeast, egg, dairy products, or artificial colors, artificial sweeteners, or artificial flavors. This product also does not contain lactose, palmitic acid, magnesium stearate, or stearic acid.

PREGNANCY
If pregnant, consult your health-care practitioner before using this product.

INTERACTIONS
Because bromelain has fibrinolytic effects, potentially inhibiting blood clotting, Phytoprofen should be used with caution or avoided in individuals on anticoagulant therapy or prior to surgery.Curcumin has been shown to reduce the therapeutic efficacy of cyclophosphamide (Cytoxan) in animal studies. In vitro research reveals curcumin decreased camptothecin-induced death of cultured breast cancer cells. Curcumin might also interfere with the absorption and efficacy of the chemotherapy drug irinotecan, used to treat colon cancer. The concurrent use of curcumin with these agents should be avoided.

ADDITIONAL WARNINGS
It is not recommended to remove the Phytoprofen powder from the capsule to take orally, as it can be irritating to the oral mucosa.