Indications
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Traditionally used in Herbal Medicine as a bitter to aid digestion, to help relieve digestive disturbances such as dyspepsia, and as a mild laxative.
Ingredients
Barberry Root, Barberry Root Extract, Goldenseal Root, Oregon Grape Root, Oregon Grape Root Extract
Quantity
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'f02_body1' => 'Traditionally used in Herbal Medicine as a bitter to aid digestion, to help relieve digestive disturbances such as <a href='/conditions/indigestion' style='text-decoration: none'>dyspepsia</a>, and as a mild laxative.',
'f02_body2' => 'Combination of berberine extracts from natural plant sources <br> Traditionally used in Herbal Medicine as a bitter to aid digestion, to help relieve digestive disturbances such as <a href='/conditions/indigestion' style='text-decoration: none'>dyspepsia</a>, and as a mild laxative <br> Includes <a href='/herbals/goldenseal' style='text-decoration: none'>goldenseal</a> root extract, <a href='/herbals/barberry' style='text-decoration: none'>barberry</a> root extract, <a href='/herbals/barberry' style='text-decoration: none'>barberry</a> root bark, <a href='/herbals/oregon-grape' style='text-decoration: none'>Oregon grape</a> root extract, and <a href='/herbals/oregon-grape' style='text-decoration: none'>Oregon grape</a> root <br> <br> Berberis Formula is a blend of <a href='/herbals/barberry' style='text-decoration: none'>barberry</a>, <a href='/herbals/goldenseal' style='text-decoration: none'>goldenseal</a> and <a href='/herbals/oregon-grape' style='text-decoration: none'>Oregon grape</a> extracts that are traditionally used in Herbal Medicine to help maintain gastrointestinal health. The main bioactive ingredient in these extracts is berberine.1,2 Recent research demonstrates that berberine inhibits bacterial attachment to the gastric mucosa.3 <br> <br> Berberine also mediates the transport of ions and water across intestinal epithelial cells.3 <br> <br> It helps maintain the balance between electrolytes and water, resulting in an anti-diarrheal effect.3 <br> <br> Berberine can increase the expression of the Na+;H+ exchanger and aquaporin 2, which help enhance the absorption of sodium and water, respectively.3,4 Berberine also promotes proper intestinal epithelial tight junction formation, and decreases the permeability of these cells to promote appropriate gastrointestinal barrier function.5 During low contractile states, berberine stimulates the jejunum through the activation of muscarinic receptors, resulting in increased intestinal motility, and a mild laxative effect.6 <br> <br> NPN 80034907 <br> 07519 <br> <br> 1. Javadzadeh, SM, Ebrahimi, A. The traditional uses and pharmacological effects of different parts Berberis Vulgaris. Sci. Agri. 2013; 1(2): 61-66. <br> 2. Siow, YL, Sarna, L, O, K. Redox regulation in health and disease - Therapeutic potential of berberine. Food Research International. 2011; 44: 2409-2417. <br> 3. Chen, C, Yu, Z, Li, Y, Fichna, J, Storr, M. Effects of Berberine in the Gastrointestinal Tract - A Review of Actions and Therapeutic Implications. The American Journal of Chinese Medicine. 2014; 42(5): 1053-1070. <br> 4. Zhang, Y, Wang, X, Sha, S, Liang, S, Zhao, L, Liu, L, Chai, N, Wang, H, Wu, K. Berberine increases the expression of NHE3 and AQP4 in sennosideA-induced diarrhoea model. Fitoterapia. 2012; 83: 1014-1022. <br> 5. Gu, L, Li, N, Gong, J, Li, Q, Zhu, W, Li, J. Berberine Ameliorates Intestinal Epithelial Tight-Junction Damage and Down-regulates Myosin Light Chain Kinase Pathways in a Mouse Model of Endotoxinemia. The Journal of Infectious Diseases. 2011; 203: 1602-1612. <br> 6. Chen, DP, Xiong, YJ, Lv, BC, Liu, FF, Wang, L, Tang, ZY, Lin, Y. Effects of berberine on rat jejunal motility. Journal of Pharmacy and Pharmacology. 2013; 65(5): 734-744.',
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'f02_body1' => 'Traditionally used in Herbal Medicine as a bitter to aid digestion, to help relieve digestive disturbances such as <a href='/conditions/indigestion' style='text-decoration: none'>dyspepsia</a>, and as a mild laxative.',
'f02_body2' => 'Combination of berberine extracts from natural plant sources <br> Traditionally used in Herbal Medicine as a bitter to aid digestion, to help relieve digestive disturbances such as <a href='/conditions/indigestion' style='text-decoration: none'>dyspepsia</a>, and as a mild laxative <br> Includes <a href='/herbals/goldenseal' style='text-decoration: none'>goldenseal</a> root extract, <a href='/herbals/barberry' style='text-decoration: none'>barberry</a> root extract, <a href='/herbals/barberry' style='text-decoration: none'>barberry</a> root bark, <a href='/herbals/oregon-grape' style='text-decoration: none'>Oregon grape</a> root extract, and <a href='/herbals/oregon-grape' style='text-decoration: none'>Oregon grape</a> root <br> <br> Berberis Formula is a blend of <a href='/herbals/barberry' style='text-decoration: none'>barberry</a>, <a href='/herbals/goldenseal' style='text-decoration: none'>goldenseal</a> and <a href='/herbals/oregon-grape' style='text-decoration: none'>Oregon grape</a> extracts that are traditionally used in Herbal Medicine to help maintain gastrointestinal health. The main bioactive ingredient in these extracts is berberine.1,2 Recent research demonstrates that berberine inhibits bacterial attachment to the gastric mucosa.3 <br> <br> Berberine also mediates the transport of ions and water across intestinal epithelial cells.3 <br> <br> It helps maintain the balance between electrolytes and water, resulting in an anti-diarrheal effect.3 <br> <br> Berberine can increase the expression of the Na+;H+ exchanger and aquaporin 2, which help enhance the absorption of sodium and water, respectively.3,4 Berberine also promotes proper intestinal epithelial tight junction formation, and decreases the permeability of these cells to promote appropriate gastrointestinal barrier function.5 During low contractile states, berberine stimulates the jejunum through the activation of muscarinic receptors, resulting in increased intestinal motility, and a mild laxative effect.6 <br> <br> NPN 80034907 <br> 07519 <br> <br> 1. Javadzadeh, SM, Ebrahimi, A. The traditional uses and pharmacological effects of different parts Berberis Vulgaris. Sci. Agri. 2013; 1(2): 61-66. <br> 2. Siow, YL, Sarna, L, O, K. Redox regulation in health and disease - Therapeutic potential of berberine. Food Research International. 2011; 44: 2409-2417. <br> 3. Chen, C, Yu, Z, Li, Y, Fichna, J, Storr, M. Effects of Berberine in the Gastrointestinal Tract - A Review of Actions and Therapeutic Implications. The American Journal of Chinese Medicine. 2014; 42(5): 1053-1070. <br> 4. Zhang, Y, Wang, X, Sha, S, Liang, S, Zhao, L, Liu, L, Chai, N, Wang, H, Wu, K. Berberine increases the expression of NHE3 and AQP4 in sennosideA-induced diarrhoea model. Fitoterapia. 2012; 83: 1014-1022. <br> 5. Gu, L, Li, N, Gong, J, Li, Q, Zhu, W, Li, J. Berberine Ameliorates Intestinal Epithelial Tight-Junction Damage and Down-regulates Myosin Light Chain Kinase Pathways in a Mouse Model of Endotoxinemia. The Journal of Infectious Diseases. 2011; 203: 1602-1612. <br> 6. Chen, DP, Xiong, YJ, Lv, BC, Liu, FF, Wang, L, Tang, ZY, Lin, Y. Effects of berberine on rat jejunal motility. Journal of Pharmacy and Pharmacology. 2013; 65(5): 734-744.',
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'f01_header2' => 'https://www.atriumpro.ca/genestra',
'f01_header3' => '',
'f01_header4' => '',
'f01_header5' => '',
'f01_header6' => '',
'zkp_ID_t' => 'RECMG10778',
'zkp_recordID_cn' => '856528',
'f03_web_image_URL' => '',
'f03_imageURL_t' => '',
'f99_hidden' => '/products/genestra-brands'
],
'[new]' => false,
'[accessible]' => [
'*' => true
],
'[dirty]' => [],
'[original]' => [],
'[virtual]' => [],
'[hasErrors]' => false,
'[errors]' => [],
'[invalid]' => [],
'[repository]' => 'Link'
}
$urlnew = null
$product_type = 'Products '
$similar_products_count = (int) 1
$flex_active_slide = (int) 0
$_key = (int) 0
$params = [
(int) 0 => ''
]
include - APP/Template/Products/index.ctp, line 2807
Cake\View\View::_evaluate() - CORE/src/View/View.php, line 1419
Cake\View\View::_render() - CORE/src/View/View.php, line 1380
Cake\View\View::render() - CORE/src/View/View.php, line 880
Cake\Controller\Controller::render() - CORE/src/Controller/Controller.php, line 796
Cake\Http\ActionDispatcher::_invoke() - CORE/src/Http/ActionDispatcher.php, line 126
Cake\Http\ActionDispatcher::dispatch() - CORE/src/Http/ActionDispatcher.php, line 94
Cake\Http\BaseApplication::__invoke() - CORE/src/Http/BaseApplication.php, line 235
Cake\Http\Runner::__invoke() - CORE/src/Http/Runner.php, line 65
Cake\Http\Runner::__invoke() - CORE/src/Http/Runner.php, line 65
Cake\Http\Middleware\CsrfProtectionMiddleware::__invoke() - CORE/src/Http/Middleware/CsrfProtectionMiddleware.php, line 108
Cake\Http\Runner::__invoke() - CORE/src/Http/Runner.php, line 65
Cake\Http\Runner::run() - CORE/src/Http/Runner.php, line 51
Cake\Routing\Middleware\RoutingMiddleware::__invoke() - CORE/src/Routing/Middleware/RoutingMiddleware.php, line 168
Cake\Http\Runner::__invoke() - CORE/src/Http/Runner.php, line 65
Cake\Routing\Middleware\AssetMiddleware::__invoke() - CORE/src/Routing/Middleware/AssetMiddleware.php, line 88
Cake\Http\Runner::__invoke() - CORE/src/Http/Runner.php, line 65
Dose
Recommended Adult Dose: Take 1 capsule 2 times daily with meals or as recommended by your healthcare practitioner. May take up to 1 week to produce beneficial effects.
Potential side effects/Safety
Risk Information: Do not use if you are pregnant or breastfeeding. Do not exceed the recommended dose. Consult your healthcare practitioner prior to use if you have a kidney disorder, blood pressure problems, heart or respiratory condition. Avoid taking with alcohol, other medications or natural health products with sedative properties. Stop use and consult your healthcare practitioner if the following symptoms occur: nausea, vomiting, drop in blood pressure or difficulty breathing. Consult your healthcare practitioner if symptoms persist or worsen. High dosages of berberine can depress respiration, stimulate intestinal smooth muscle and reduce bronchial constriction.