Goldenseal was first used by the First Nations people of North America. The root is rich in isoquinoline alkaloids (e.g. hydrastine, berberine) that function as broad-acting antimicrobials. In addition, it contains other phytochemicals that work synergistically to decrease drug resistance.
Research supports it possess antibacterial, antiviral, antifungal and anti-parasitic activity. Goldenseal has been referred to by North American herbalists as “King of the Mucous Membranes” because it has an affinity for infections of both the gastrointestinal tract (e.g. infectious diarrhoea) and respiratory tract (e.g. sinusitis, colds, influenza)
Goldenseal is a strong digestive bitter and stimulates the release of stomach acid, bile and pancreatic enzymes, thus making it useful for indigestion and constipation.
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