• Flora SAP can help prevent and treat recurrent vulvovaginal candidiasis and bacterial vaginosis.
• Flora SAP may help prevent growth of Group-B streptococci (GBS) during pregnancy.
• Flora SAP can be used to help prevent spontaneous preterm delivery associated with intrauterine infection.
• Flora SAP can be used to help prevent recurrent urinary tract infections.
Each capsule of Flora SAP contains:
L. rhamnosus... 3 billion
L. acidophilus ... 3 billion
L. fermentum... 3 billion
L. casei... 50 million
L. thermophilus... 50 million
Flora SAP contains no artificial flavours, colours, soy, gluten or preservatives.
Genitourinary infections affect more than 1 billion women worldwide every year and are the most common reason a women will see a gynecologist.(1) These infections can be bacterial in nature (called bacterial vaginosis) or fungal in nature (called vulvovaginal candidiasis). The types of bacteria in the vaginal canal will fluctuate based on a variety of factors including hormone levels, diet, sexual contact and douching; however, the basic composition is Lactobacilli-dominant in healthy females.(1) It is the depletion of these healthy organisms that can leave a woman prone to urinary and vaginal infections.(1) There are probiotic bacteria that can help in modulating the immune system and displacing pathogens that can cause these infections.(2) A healthy vaginal canal should be colonized by Lactobacilli as the dominant bacterial species. Lactobacilli produce H2O2, which helps maintain a vaginal pH close to 4.0, which is essential for vaginal health.(3) Maintenance of a vaginal pH around 4.0 decreases a woman's chances of developing vaginosis.(3)
Use one capsule inserted vaginally per night for 10 days or as recommended by your health care
Lactobacilli are considered to be safe because they are components of the commensal human
flora and due to the fact that they have been used for a long time in food industry and in douches,
even by pregnant women, without harmful effects.(3)
1. Reid, G. “Probiotic Lactobacilli for urogenital health in women”. Journal of Clinical
Gastroenterology 42, Suppl 3 Pt 2 (2008): S234–S236.
2. Reid, G., J. Dols, and W. Miller. “Targeting the vaginal microbiota with probiotics as a
means to counteract infections”. Current Opinion in Clinical Nutrition and Metabolic Care
12, No. 6 (2009): 583–587.
3. Krauss-Silva, L., M.E. Moreira, M.B. Alves, et al. “Randomized controlled trial of probiotics
for the prevention of spontaneous preterm delivery associated with intrauterine infection:
study protocol”. Reproductive Health 7 (2010): 14.
4. Stapleton, A.E., M. Au-Yeung, T.M. Hooton, et al. “Randomized, placebo-controlled phase
2 trial of a Lactobacillus crispatus probiotic given intravaginally for prevention of recurrent
urinary tract infection”. Clinical Infectious Diseases 52, No. 10 (2011): 1212–1217.
5. Delia, A., G. Morgante, G. Rago, et al. “[Effectiveness of oral administration of Lactobacillus
paracasei subsp. paracasei F19 in association with vaginal suppositories of Lactobacillus
acidofilus in the treatment of vaginosis and in the prevention of recurrent vaginitis]”.
Minerva Ginecologica 58, No. 3 (2006): 227–231.
6. Marcone, V., G. Rocca, M. Lichtner, and E. Calzolari. “Long-term vaginal administration
of Lactobacillus rhamnosus as a complementary approach to management of bacterial
vaginosis”. International Journal of Gynaecology and Obstetrics 110, No. 3 (2010): 223–226.
7. Coudeyras, S., G. Jugie, M. Vermerie, and C. Forestier. “Adhesion of human probiotic
Lactobacillus rhamnosus to cervical and vaginal cells and interaction with vaginosisassociated
pathogens”. Infectious Diseases in Obstetrics and Gynecology 2008 (2008):
8. Falagas, M.E., G.I. Betsi, and S. Athanasiou. “Probiotics for prevention of recurrent
vulvovaginal candidiasis: a review”. The Journal of Antimicrobial Chemotherapy 58, No. 2
9. Fichorova, R.N., A.B. Onderdonk, H. Yamamoto, et al; Extremely Low Gestation Age
Newborns (ELGAN) Study Investigators. “Maternal microbe-specific modulation of
inflammatory response in extremely low-gestational-age newborns”. mBio 2, No. 1 (2011):
10. Z Á rate, G. and M.E. Nader-Macias. “Influence of probiotic vaginal lactobacilli on in
vitro adhesion of urogenital pathogens to vaginal epithelial cells”. Letters in Applied
Microbiology 43, No. 2 (2006): 174–180.
11. AÇikgÖz, Z.C., S. Gamberzade, S. GÖÇer, and P. Ceylan. “[Inhibitor effect of vaginal
lactobacilli on group B streptococci”. Mikrobiyoloji BÜlteni 39, No. 1 (2005): 17–23.
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