• Berberine SAP may be effective in reducing non-alcoholic fatty liver disease (NAFLD);
• Berberine SAP may assist in regulating symptoms associated with metabolic syndrome;
• Berberine SAP supports healthy cholesterol and glucose levels in patients with type-2
diabetes or hypercholesterolemia;
• Berberine SAP supports healthy microbial activity against bacterial, viruses, helminthes, and
fungi, without having a negative impact on beneficial bacteria.
Each capsule contains:
Berberine hydrochloride 300 mg
Goldenseal ... 150mg
Contains no: Preservatives, artificial flavor or color, sugar, dairy, starch, wheat, gluten, yeast, soy, citrus, or eggs.
Berberine is an active constituent found in a variety of species of plants. Newer studies have found berberine has biological effects in several pathways in the body, indicating it may be a potential treatment for metabolic syndrome. Metabolic syndrome is hypothesized as beginning with an accumulation of lipids in non-adipose tissues, known as non-alcoholic fatty liver disease (NAFLD). Berberine also has studies supporting its ability to reduce symptoms associated with NAFLD, as well as showing significant antidiabetic effects and lipid-lowering capability.[2, 3, 4] Historically, berberine has been used for its antimicrobial activity, as berberine is active against a wide range of organisms including bacterial viruses, fungi, helminthes, and chlamydia.[1 ]
Take 1 capsule one to three times daily or as directed by your health care practitioner.
There is a long history of safe usage of berberine clinically. However, some adverse effects have been reported, including gastrointestinal concerns, allergic skin reactions, and arrhythmia. There are some reports that indicate berberine may induce apoptosis in hepatoma cells; however, these cytotoxic effects were not seen in healthy hepatocytes.
In a recent study, berberine supplemented in oral dosages of 500 mg three times per day was associated with gastrointestinal symptoms in 34.5% of participants. However, at the reduced dose of 300 mg of berberine three times per day, gastrointestinal side effects were eliminated while observing similar beneficial effect on glucose and lipid control. For this reason and optimal patient safety, Berberine SAP is dosed at 300 mg per capsule of berberine hydrochloride.
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