• Megaloblastic anemia
• Cardiovascular health
• Neural tube defects
What Is It?
Folic acid (or folate) is vitamin B9, a water-soluble vitamin that plays a key role in DNA and RNA synthesis, red blood cell production, the metabolism of proteins, and healthy genetic expression. BioFolate contains L-5-methyltetrahydrofolate (L-5-MTHF), the active form of folate that is used in the body. Unlike the folates found in dark green leafy vegetables, oranges and liver, supplemental forms of folic acid do not need to be enzymatically altered prior to absorption, and are therefore absorbed twice as efficiently as natural folates. In addition, a large percentage of the population lacks the ability to convert dietary folate into the biologically active form, which can cause a folate deficiency. BioFolate also contains a small amount of vitamin B12 in the active form of methylcobalamin, since folate supplementation can mask a vitamin B12 deficiency.
What Does It Do?Primary Uses: Supplementing with L-5-MTHF helps prevent a folic acid deficiency. Folate deficiency can cause a number of health problems, of which the most documented is neural tube defects in developing infants. Symptoms of deficiency include: weakness, fatigue, irritability, headaches, difficulties in cognitive function, mood imbalances, cramps, palpitations, shortness of breath, and can lead to more serious health problems.Secondary Uses: Some conditions can actually lead to secondary folate deficiencies through decreased absorption or an increase in the body's demand for folate. These include alcoholism, Crohn's disease, lymphoma or amyloidosis of the small intestine, diabetic enteropathy, gluten sensitivity, sickle cell disease, chronic exfoliative skin disorders and of course, pregnancy.
Who Should Take It?
Expecting mothers or other persons who are at risk of being deficient or low in folic acid could benefit from taking Biofolate. It may also benefit people with mood disorders and those who are at risk for the various diseases mentioned above.
Take 1 capsule daily with food, or as directed by a qualified health care practitioner.
CAUTION: Folate supplementation can mask a vitamin B12 deficiency. Consult a health care practitioner prior to use if you are uncertain whether or not you are taking adequate vitamin B12 or if you are pregnant or breastfeeding.
5-methyltetrahydrofolate. Monograph. Altern Med Rev. 2006 Dec;11(4):330-7. Review.
Ulrich CM, Potter JD. Folate and cancer–timing is everything. JAMA 2007 Jun 6;297(21):2408-9.
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