What Is It?
Magnesium malate is a true chelate of magnesium and malic acid. Malic acid is ionized in the body to form malate, which is a key intermediate in the energy production cycle that makes ATP, the fuel that allows cells to function. Magnesium is a mineral that also supports the energy production cycle among many other functions such as allowing the relaxation of muscles after a contraction.
What Does It Do?
Primary Uses: Low levels of ATP are commonly found in people suffering with fibromyalgia and are believed to play a significant role in the physical and mental symptoms of the condition. Magnesium plays a critical role in the production and stabilization of ATP. It activates almost all the enzymes that ultimately transform fats and sugars into useable energy. A lack of ATP is also thought responsible for the muscle weakness and pain that accompanies the disease. Studies have also found that magnesium malate reduces the symptoms of fibromyalgia and chronic fatigue sufferers.
Secondary Uses: The brain stores 20% of total body ATP. Low levels of ATP may cause a decline in cognitive function – the “brain fog” so commonly reported, in which victims find themselves struggling to concentrate and often forgetting simple thoughts and tasks.
Who Should Take It?
Those who have been diagnosed with fibromyalgia or chronic fatigue may find some relief from its mental and physical symptoms using magnesium malate, as well as those who have not been diagnosed but have low energy levels and chronic fatigue.
Take 1-3 capsules daily with food, or as directed by a qualified health care practitioner. Increase dosage gradually.
Cautions: None known.
Russell IJ, Michalek JE, Flechas JD, Abraham GE. Treatment of fibromyalgia syndrome with Super Malic: a randomized, double blind, placebo controlled, crossover pilot study. J Rheumatol 1995 May; 22(5): 953-8.
Cox IM, Campbell MJ, Dowson DI. Red blood cell magnesium levels and the chronic fatigue syndrome (ME); a case control study and a randomised controlled trial. Lancet 1991 Mar 30; 337(8744): 757-60.
Eisinger J, Plantamura A, Marie PA, Ayavou T. Selenium and magnesium status in fibromyalgia. Magnes Res 1994 Dec; 7(3-4): 285-8.
Abraham GE, Flechas JD. Management of Fibromyalgia: Rationale for the Use of Magnesium and Malic Acid. Journal of Nutritional Medicine (1992) 3, 49-59.
Romano TJ, Stiller JW. Magnesium deficiency in fibromyalgia syndrome. J Nutr Med. 1994; 4(2): 165-7.
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