Indications

• Anti-Aging
• Normal cell growth
• Healthy cellular function
• Sports nutrition

Ingredients

Serving Size: 1 Capsule... %DV
L-Carnosine... 500 mg... †

† Daily Value not established

Description

Carnosine is a dipeptide (a combination of two amino acids) found in human tissues that has a wide range of health benefits. It is primarily known as an anti-aging nutrient and is found naturally in small amounts in animal meats. Pre-clinical studies have found impressive results in carnosine's ability to reverse cellular aging. It is a powerful antioxidant and inhibits protein glycation; therefore addressing two of the most important drivers behind the aging process. Carnosine protects cells and helps maintain healthy cellular function by getting rid of damaged proteins that make cells old and dysfunctional. Studies in human subjects have also found carnosine to enhance exercise performance and tissue repair due to its effects on cellular rejuvenation and protein maintenance. A unique mechanism of carnosine is that it regulates acidity and alkalinity inside the cell, optimizing the cellular environment.

Brain health is another promising application for carnosine. A study on autistic children found that autistic behaviour improved with carnosine supplementation. There is exciting new research being conducted using carnosine in areas such as brain health, stroke recovery, anti-aging, cataract treatment, immune stimulation, athletic performance and many others. Anti-aging enthusiasts, vegetarians, and athletes are those who will benefit most from carnosine. AOR's Carnosine-500 is one of the only stand-alone formulations available on the market that contain an evidence-based dose of this powerful antioxidant.

Quantity

60 VEGI-CAPS

Dose

Take 1 capsule daily without food, or as directed by a qualified health care practitioner.

Potential side effects/Safety

CAUTION: Consult a health care practitioner if you are pregnant or breastfeeding, or for use beyond 8 weeks.

References

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Chez MG, Buchanan CP, Aimonovitch MC, Becker M, Schaefer K, Black C and Komen J. Double-blind, placebo-controlled study of L-carnosine supplementation in children with autistic spectrum disorder. J Child Neurol 2002;17;833-837.

Derave W, Ozdemir MS, Harris R, Pottier A, Reyngoudt H, Koppo K, Wise JA, Achten E. Beta-alanine supplementation augments muscle carnosine content and attenuates fatigue during repeated isokinetic contraction bouts in trained sprinters. J Appl Physiol. 2007 Aug 9

Hill CA, Harris RC, Kim HJ, Harris BD, Sale C, Boobis LH, Kim CK, Wise JA. Influence of beta-alanine supplementation on skeletal muscle carnosine concentrations and high intensity cycling capacity. Amino Acids. 2007 Feb;32(2):225-33.

Hipkiss AR, Brownson C, Carrier MJ. “
Carnosine, the anti-ageing, anti-oxidant dipeptide, may react with protein carbonyl groups.”

Mech Ageing Dev. 2001 Sep 15; 122(13): 1431-45.

Holliday R, McFarland GA. “
Inhibition of the growth of transformed and neoplastic cells by the dipeptide carnosine.”

Br J Cancer. 1996 Apr; 73(8): 966-71.

McFarland GA, Holliday R. “
Retardation of the senescence of cultured human diploid fibroblasts by carnosine.”

Exp Cell Res. 1994 Jun; 212(2): 167-75.

McFarland GA, Holliday R. “
Further evidence for the rejuvenating effects of the dipeptide L-carnosine on cultured human diploid fibroblasts.”

Exp Gerontol. 1999 Jan; 34(1): 35-45.

Nagai K, Suda T. “
Antineoplastic effects of carnosine and beta-alanine–physiological considerations of its antineoplastic effects.”

Nippon Seirigaku Zasshi. 1986; 48(11): 741-7.

Stvolinsky S, Kukley M, Dobrota D, Mezesova V, Boldyrev A. “
Carnosine protects rats under global ischemia.”

Brain Res Bull. 2000 Nov 1; 53(4): 445-8.

Yuneva MO, Bulygina ER, Gallant SC, Kramarenko GG, Stvolinsky SL, Semyonova ML, Boldyrev AA. “
Effect of carnosine on age-induced changes in senescence-accelerated mice.”

J Anti-Aging Med. 1999 Winter; 2(4): 337-42.